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KMID : 0882420170920040419
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Korean Journal of Medicine
2017 Volume.92 No. 4 p.419 ~ p.423
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Community-onset Necrotizing Fasciitis Caused by Extended-spectrum Beta-lactamase-producing Eshcerichia coli
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Jang Ji-Hye
Kim Chang-Wook
Kim Se-Young
Pack Yun-Jung
Seo Min-Ji
Kim Seon-A
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Abstract
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Necrotizing fasciitis (NF) is an uncommon but fatal infectious disorder that rapidly destroys connective tissue, causing extensive necrosis, severe sepsis, multiple organ failure, and death. NF is more common in patients with comorbid medical conditions. Most NF is caused by bacteria extending from localized skin infections, or remote bacteremia. Escherichia coli (E. coli) has been isolated from polymicrobial NF, but is rarely causative of monomicrobial NF. In addition, NF attributable to community-onset, extended-spectrum beta-lactamase (ESBL)-producing E. coli has not been described previously. As ESBL-producing E. coli are becoming significant pathogens of community-acquired infections worldwide, we report an exceptional case of community-onset NF attributable to monomicrobial ESBL-producing E. coli in a patient with liver cirrhosis.
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KEYWORD
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Fasciitis, Necrotizing, Beta-lactamases, Escherichia coli, Community-acquired Infections
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